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Letter to the Editor|Articles in Press

Strategy to track and combat deep sternal wound infection caused by Mycobacterium farcinogenes

  • Author Footnotes
    † Yu Zhou and Tingting Xia contributed equally to this work.
    Y. Zhou
    Footnotes
    † Yu Zhou and Tingting Xia contributed equally to this work.
    Affiliations
    Department of Laboratory Medicine, Second Medical Centre of PLA General Hospital, Beijing, People's Republic of China
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  • Author Footnotes
    † Yu Zhou and Tingting Xia contributed equally to this work.
    T. Xia
    Footnotes
    † Yu Zhou and Tingting Xia contributed equally to this work.
    Affiliations
    Department of Disease Prevention and Control, Hainan Hospital of PLA General Hospital, Sanya, Hainan, People's Republic of China
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  • M. Du
    Affiliations
    Department of Disease Prevention and Control, First Medical Centre of PLA General Hospital, Beijing, People's Republic of China
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  • H. Cao
    Affiliations
    Department of Laboratory Medicine, Second Medical Centre of PLA General Hospital, Beijing, People's Republic of China
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  • Q. Zheng
    Affiliations
    Department of Laboratory Medicine, Second Medical Centre of PLA General Hospital, Beijing, People's Republic of China
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  • J. Yang
    Affiliations
    Department of Disease Prevention and Control, Hainan Hospital of PLA General Hospital, Sanya, Hainan, People's Republic of China
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  • Z. Yan
    Correspondence
    Corresponding author. Address: Department of Disease Prevention and Control, Second Medical Centre of PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, People's Republic of China. Tel./fax: +86 10 68295439.
    Affiliations
    Department of Disease Prevention and Control, Hainan Hospital of PLA General Hospital, Sanya, Hainan, People's Republic of China

    Department of Disease Prevention and Control, Second Medical Centre of PLA General Hospital, Beijing, People's Republic of China
    Search for articles by this author
  • Author Footnotes
    † Yu Zhou and Tingting Xia contributed equally to this work.
Published:March 29, 2023DOI:https://doi.org/10.1016/j.jhin.2023.03.016
      We present the first reported case of a patient who developed a postoperative sternal wound infection due to Mycobacterium farcinogenes. The microbe is a rapid grower suggestive of atypical mycobacterium, and the principal causative agent of bovine farcy. M. farcinogenes is an uncommon cause of human disease and only a few cases have been described to date [
      • Al Farsi F.
      • Al Adawi B.
      • Ba Tahir H.
      • Al Mutani M.
      • Adikaram C.
      • Al Siyabi T.
      • et al.
      Mycobacterium farcinogenes osteomyelitis of the proximal tibia: a case report.
      ]. To the best of our knowledge, this is the first report of a sternal wound infection caused by M. farcinogenes. On 4th March 2021, a 69-year-old male patient underwent a median sternotomy for a coronary artery bypass graft. Subsequently, he became febrile (38.1 °C) and complained of sternal pain on postoperative day 24. The patient developed a deep sternal wound infection (DSWI) diagnosed by surgeons according to published criteria [
      • Chen C.
      • Gao Y.
      • Zhao D.
      • Ma Z.
      • Su Y.
      • Mo R.
      Deep sternal wound infection and pectoralis major muscle flap reconstruction: a single-center 20-year retrospective study.
      ]. The simplified timeline for DSWI history of this patient is shown in Figure 1.
      Figure 1
      Figure 1Simplified timeline for deep sternal wound infection history of the case patient. NWPT, negative pressure wound therapy; CT, computed tomography; PET, positron emission tomography.
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