We appreciate the contribution of Black and colleagues [
[1]
] in relation to our paper on biocide resistance in Acinetobacter baumannii [
Black E, Weber J, Theelen M, Biocide resistance in Acinetobacter baumannii: Appraising the Mechanisms. Letter to Editor, https://www.journalofhospitalinfection.com/article/S0195-6701(21)00334-0/fulltext#%20
[2]
]. European standard (NF EN) including EN 14885 and others EN 1276, prEN 12054, EN
13727 etc., have been applied as quantitative kill test for specific bacteria [
- Milani E.S.
- Hasani A.
- Varschochi M.
- Sadeghi J.
- Memar M.Y.
- Hasani A.
Biocide resistance in Acinetobacter baumannii: Appraising the Mechanisms.
J Hosp Infection. 2021; (Published:September 21, 2021)https://doi.org/10.1016/j.jhin.2021.09.010
[2]
,
- Milani E.S.
- Hasani A.
- Varschochi M.
- Sadeghi J.
- Memar M.Y.
- Hasani A.
Biocide resistance in Acinetobacter baumannii: Appraising the Mechanisms.
J Hosp Infection. 2021; (Published:September 21, 2021)https://doi.org/10.1016/j.jhin.2021.09.010
[3]
] whereby the number of viable bacteria is determined and the reduction in viability
is calculated. The test has the main advantage that it applies to all types of disinfectants
and allows testing of the effects of temperature and interfering substances [
[3]
]. This test specifies effectiveness of all disinfectants at recommended use concentrations
and contact times [
[3]
,
[4]
]. However, it is more time consuming and less reproducible than minimum inhibitory
concentration (MIC) determination [
[5]
]. Moreover, resistance in bacteria is a phenomenon which can be achieved by mutation,
acquisition of new genetic information by horizontal gene transfer, expression of
previously silent genes, growth in a biofilm and other poorly defined phenotypic alterations
which can be give rise to a transiently resistant phenotype [
[6]
].To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Hospital InfectionAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
Black E, Weber J, Theelen M, Biocide resistance in Acinetobacter baumannii: Appraising the Mechanisms. Letter to Editor, https://www.journalofhospitalinfection.com/article/S0195-6701(21)00334-0/fulltext#%20
- Biocide resistance in Acinetobacter baumannii: Appraising the Mechanisms.J Hosp Infection. 2021; (Published:September 21, 2021)https://doi.org/10.1016/j.jhin.2021.09.010
- Does microbial resistance or adaptation to biocides create a hazard in infection prevention and control?.Journal of Hospital Infection. 2010; 76: 200-205
- Resistance to disinfectants in epidemiologically defined clinical isolates of Acinetobacter baumannii.Journal of Hospital Infection. 2007; 66: 174-181
- Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds—a critical review.International Journal of Antimicrobial Agents. 2012; 39: 381-389
- Disinfectant resistance mechanisms, cross- resistance and co-resistance.International Biodeterioration and Biodegradation. 2003; 51: 271-276
- Biocide susceptibility testing of bacteria: Development of a broth microdilution method.Veterinary Microbiology. 2020; 248: 108791
Article info
Publication history
Accepted:
October 7,
2021
Received:
October 6,
2021
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2021 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
