Compressed sodium chloride as a fast-acting antimicrobial surface: results of a pilot study


      Antimicrobial surfaces are currently being studied as an aid to reduce transmission of pathogens leading to healthcare-associated infections (HAIs). Among the most harmful and costly pathogens that cause HAIs is meticillin-resistant Staphylococcus aureus (MRSA). Currently available and previously investigated antimicrobial surface technologies that are effective against MRSA (e.g. copper alloy surfaces) take 30min to several hours to achieve significant reduction. This article presents a new antimicrobial surface technology made of compressed sodium chloride that reduces MRSA 20–30 times faster than copper alloy surfaces.


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        • Navarro M.B.
        • Huttner B.
        • Harbarth S.
        Methicillin-resistant Staphylococcus aureus control in the 21st century: beyond the acute care hospital.
        Curr Opin Infect Dis. 2008; 21: 372-379
        • Page K.
        • Wilson M.
        • Parkin I.P.
        Antimicrobial surfaces and their potential in reducing the role of the inanimate environment in the incidence of hospital-acquired infections.
        J Mater Chem. 2009; 19: 3819-3831
        • Klevens R.M.
        • Edwards J.R.
        • Richards C.L.
        • et al.
        Estimating health care-associated infections and deaths in U.S. hospitals, 2002.
        Public Health Rep. 2007; 122: 160-166
        • Scott R.D.
        The direct medical costs of healthcare-associated infections in U.S. hospitals and the benefits of prevention.
        (Publication CS200891-A) Centers for Disease Control and Prevention, Atlanta, GA2009
        • Dancer S.J.
        Controlling hospital-acquired infection: focus on the role of the environment and new technologies for decontamination.
        Clin Microbiol Rev. 2014; 27: 665-690
        • Centers for Disease Control and Prevention
        Active bacterial core surveillance report, Emerging Infections Program Network. Methicillin-resistant Staphylococcus aureus.
        CDC, Atlanta, GA2012
        • Salgado C.D.
        • Sepkowitz K.A.
        • John J.F.
        • et al.
        Copper surfaces reduce the rate of healthcare-acquired infections in the intensive care unit.
        Infect Control Hosp Epidemiol. 2013; 34: 479-486
        • Grass G.
        • Rensing C.
        • Solioz M.
        Metallic copper as an antimicrobial surface.
        Appl Environ Microbiol. 2011; 77: 1541-1547
        • Noyce J.O.
        • Michels H.
        • Keevil C.W.
        Potential use of copper surfaces to reduce survival of epidemic meticillin-resistant Staphylococcus aureus in the healthcare environment.
        J Hosp Infect. 2006; 63: 289-297