Advertisement
Letter to the Editor| Volume 93, ISSUE 3, P314-315, July 2016

Download started.

Ok

Increasing incidence of multidrug-resistant Gram-negative septicaemia during induction therapy of acute myeloid leukaemia

Published:April 29, 2016DOI:https://doi.org/10.1016/j.jhin.2016.04.012
Increasing incidence of multidrug-resistant Gram-negative septicaemia during induction therapy of acute myeloid leukaemia
Previous ArticleFacial hair – what about clinical microbiology technicians?
Next ArticleInfluence of risk assessment inspection on the prevention of nosocomial infection
      Multidrug-resistant Gram-negative bacterial (MDR-GNB) septicaemia is an emerging global challenge. Patients with cancer with compromised immunity and frequent contact with the health system are more vulnerable to this problem. Recent reports from India document high levels of carbapenem resistance (25–50%) among bacterial isolates from patients with cancer.
      • Bhattacharya S.
      • Goel G.
      • Mukherjee S.
      • Bhaumik J.
      • Chandy M.
      Epidemiology of antimicrobial resistance in an oncology center in eastern India.
      Infect Control Hosp Epidemiol. 2015; 36: 864-866
      , 
      • Ghosh I.
      • Raina V.
      • Kumar L.
      • et al.
      Profile of infections and outcome in high-risk febrile neutropenia: experience from a tertiary care cancer center in India.
      Med Oncol Northwood Lond Engl. 2012; 29: 1354-1360
      Induction therapy of acute myeloid leukemia (AML) is characterized by significant mortality due to septicaemia which is compounded by MDR infections.
      • Philip C.
      • George B.
      • Ganapule A.
      • et al.
      Acute myeloid leukaemia: challenges and real world data from India.
      Br J Haematol. 2015; 170: 110-117
      We report our recent experience with MDR-GNB sepsis during induction therapy of AML.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Hospital Infection
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Bhattacharya S.
        • Goel G.
        • Mukherjee S.
        • Bhaumik J.
        • Chandy M.
        Epidemiology of antimicrobial resistance in an oncology center in eastern India.
        Infect Control Hosp Epidemiol. 2015; 36: 864-866
        View in Article
        • Ghosh I.
        • Raina V.
        • Kumar L.
        • et al.
        Profile of infections and outcome in high-risk febrile neutropenia: experience from a tertiary care cancer center in India.
        Med Oncol Northwood Lond Engl. 2012; 29: 1354-1360
        View in Article
        • Philip C.
        • George B.
        • Ganapule A.
        • et al.
        Acute myeloid leukaemia: challenges and real world data from India.
        Br J Haematol. 2015; 170: 110-117
        View in Article
        • Mirrett S.
        • Hanson K.E.
        • Reller L.B.
        Controlled clinical comparison of VersaTREK and BacT/ALERT blood culture systems.
        J Clin Microbiol. 2007; 45: 299-302
        View in Article
        • Trubiano J.A.
        • Worth L.J.
        • Thursky K.A.
        • Slavin M.A.
        The prevention and management of infections due to multidrug resistant organisms in haematology patients.
        Br J Clin Pharmacol. 2015; 79: 195-207
        View in Article
        • Porwal R.
        • Gopalakrishnan R.
        • Rajesh N.J.
        • Ramasubramanian V.
        Carbapenem resistant Gram-negative bacteremia in an Indian intensive care unit: a review of the clinical profile and treatment outcome of 50 patients.
        Indian J Crit Care Med. 2014; 18: 750-753
        View in Article

      Article info

      Publication history

      Published online: April 29, 2016
      Accepted: April 20, 2016
      Received: April 18, 2016

      Identification

      DOI: https://doi.org/10.1016/j.jhin.2016.04.012

      Copyright

      © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

      ScienceDirect

      Access this article on ScienceDirect

      The content on this site is intended for healthcare professionals.


      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties.


      RELX